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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'fe5e49a73c10a6994522d3e44b327f8aa64d7dc9d91ad19032e6043fa3a68edf' 
  AND token = 'oudloXWAi4X6TC+6F8iheeNUvf2l+992GJlmpr8ROak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}