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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5874f620af6619b70bad3f446eaa6c50309a0e3fedceadda1817f305741b3da6' 
  AND token = 'NXMeiiEyXQVx/OjCCOw4TCzW3+vxy9Xv8wecW0ppKdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}