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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ea378289558ec1233896967efbb379f8581635ffb2a7d6806d55c5362885c42a' 
  AND token = 'xXq/c0fBI648z+Wjg3Ik87p6rupDwfHlheefjxBHujA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}