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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22052ac0ef214f990cc9ea4069ab2c583e06b3a2208492f15afb24731e705bea' 
  AND token = 'QwTNWYlpq/tBvweqlvd2sLvtC/jKYttlaBOV1NsOr50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}