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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '25fda6a7d706f55cd310f832742d51333178bb848ce755a9e54f98e509ee9aa9' 
  AND token = 'NoK/gRoOouifpqZNJ/fFxVcRXNNtV0NksyQvRofvxXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}