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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e2a00e97de48fd6d2d90d24a78ce0a2ed6f82a1aca004425f4c647c7d998e676' 
  AND token = 'ufEA/0sQQbEJRYhxXYCi2gtOXunRuhnsJ57dr+UC28Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}