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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'da220d7916956db06640f21e67efd3456517a3e8095a8e868e8f4fe2e997e8ab' 
  AND token = 't9Q5PFhCujm6x5NU+N/GxBhJgm6d5PiaUFeIU1NBZss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}