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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '588a282ec95f37d3f3c3dc7190a4d32a47ba6ab8647d247c3cae96429170eeb3' 
  AND token = 'HMp7YZ8qXgVzSZe8sOYMVGuAiTymTVvm12dnkxiLkbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}