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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '837e4cfe52cff8aca83c1a890ff0ec5b943f60184834b118704e3004a7b51572' 
  AND token = '6CNPsUi/XY1+enWH9JnX43zM0cMWJG2CXtHwFY3FI8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}