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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'fcb4bc3b7a6f966ad27996f80f8d420488deeb78e682427f6200a09eff7efeb1' 
  AND token = 'RNXpWPDSaIQe7XUrRFdBLuS+oSYziBJ+4Od9pn9gBW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}