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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5c9268650b49e5621ba44eefa3b0c9454649f46ed9d1b40eb351098c8ee4c379' 
  AND token = 'IvC2oksar1jU4rDsZ1GZhRK8Cl+e4ctSFRAe83P0uuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}