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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '549de4ff27a496cb2951b09f21576deaa1cd347057d1590e6e24bd206bc02a67' 
  AND token = 'TzSxpxsi9cSHUrgKCe0TLVXLXNYU5pLyIcCyDezvdFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}