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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e54d281f987da9c67cea33db1a0b3d166b2f56ee53b7c0010a7e78a4c212741d' 
  AND token = 'hMc+3jVSmskVLLE+uS3scRlOMSNKff3yy9dnLIExqF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}