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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2617e2c8facd3494f3178bd6809b1d3f4a60bde682a2a4244837dac858f58d4a' 
  AND token = 'EAPrwn4ljlA03/gRBbHS/pB3Hwryp4kz07fye8NkoLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}