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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '728c255822f8a8c3765906e2dba547660fae86b180b8e356da9ef4e8be026506' 
  AND token = 'rXv59eR08Lqd02z+OQAp+UYI8g7OsUF2zfelYp0q/KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}