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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '00cde88f027f70c100473737024e389b2a7667bba179d1e32223e11203b2540a' 
  AND token = 'lzjmNXmcyW3TLdvzjNzaCSlA7EZAjan3F5fi+ZjlYAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}