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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1f4d5ee378cd90893869275c8d93e186ff96a5da510e989cce7da56de1a2612f' 
  AND token = 'hzryNDKdpH9dwfAlgwyXSbs+WkcFOmpmg/OJn3M2GyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}