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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5de00ebd11655cc6c350ce364cc9f184c345ecf177f9460e5fb0c444c5fe11d5' 
  AND token = 'ww45SI6szLUQHMPWGmHwnFVSNqSdHAZSeAt+60JgOe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}