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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '541f11943f770727fcdd5bb3c342615e14a36059daffed030cad4cf5bc715996' 
  AND token = 'up+2OV72fOQZ3u8hES0mTFXMgY07ayeHREftND/SxCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}