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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '80a93cb641fdfe8970d3a0e414d2f5390434c85784f265e1050e1a56c2f4f795' 
  AND token = 'l9jeXeXiiJDQECRwznim5b+OWYbz5T6JjcR1VCReE9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}