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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8c279132db7560b77a39141255551920c9713f8109c57fd4ac1ee80a3ba75551' 
  AND token = 'f+QN/rz10Rr9WXb0olMm66fSxmw1CEN8GWUFb1ohWFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}