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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '16ec67781f93fc36fb62b87696d39739e8f05ac4bda1be09c52a0a2ba2da0c60' 
  AND token = 'L/Bxp/bb8dUd2MbgwjY5eyUgkedEtkP7h4zRU13zRbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}