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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e27e09d3181f1dac2126972230871bf00f24cd47f7d4372df50a233f79fabe58' 
  AND token = '2u2SLGTo1HHVXmSHe1TqFrxNe+ywBYKx6+Byq7BDl0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}