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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a50751923b55eba5d56dd7451851a4d8bdff1924bea06f7134d7518791d3d1f9' 
  AND token = 'EJD2ydlImPLUC8xAZd6XwJB5/N9Yb0de2kHqfLIlPq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}