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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '72b0d5c449b21f9eae010d09399a3a911c53b6c9cbb7d25adc3b47bc05561698' 
  AND token = 't3lX8F3tptBSBgbIaJ4xzpAFecQCfN0dDcU87V5Rqh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}