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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '18e308c57cc3dd96bf1709e2eddb11bab0398f61deae604f590161fa42214be2' 
  AND token = '9Iv16rXIyIXaIA8lzVPTIbxgjT2UJ/fwYz01PXSNTE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}