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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '78a523d022df2386d7bfe1a072bd120e844248dbcdfc0f85460d7572c9834c6b' 
  AND token = '++s3Fd51mY3tmcTmtZClVeSmTZcb3eJFmoHKSx+ji9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}