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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '53d34baa2baf8d0b0a89be3560483ebad690f34ce683a06a371ab0bbe137f058' 
  AND token = 'W/Iftzn3PZJUI/2+F43x1TaXsfwdCYSrYFkjY4roBLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}