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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a55d2721744223c79728b2d22ddddd863c2952626c473c52edbbb05e190f06a0' 
  AND token = 'sxsvHF+2oM0HjqgzITnHb0C6DzbFIEtT0XDAHOkWibo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}