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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '80219f645d9c78608d395b6c56f04af38b5b2abc5375a43b8aebddc61da53f23' 
  AND token = 'PQMtkj65uwLWseEiYMRf5vjzaabQ/69HtEZOCgxbwXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}