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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1abc97d69ba8a4932018f1dcaa15452bd39d5a760eac7687e617ae04b70378ba' 
  AND token = 'UAUGoLFdaMiydYYEK0shXhQyGYqmcbbrakORYCtzs6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}