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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2515325e6d2e226c132b81f833241415a01f0351b3042d8f99e436256126bf3b' 
  AND token = 'y+PagQXBE5F44AC5tHqXAAP1S/jU/mohyFzXuPCR2sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}