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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'adb7eaa829cc08e51e0c358d8c573932c468328b07e978296a7c3a263e248f73' 
  AND token = 'wQRa78CpotiryqkJOdD4CuoEnudjrtGPDseUepgv5Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}