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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4ead4ce218ea7a1ea9cbc3e56599829ce44eca80198faafeac8438676d834c49' 
  AND token = '8fMbpCt5gHA1LzVmmElX89HL8HJbEiX78/8E3SA2nTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}