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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c8e6c0559cdf445d4e005442a6851254848a1afe527b39f956fde1628e9deac9' 
  AND token = 'tDwEE7Nm7xElCUABVYFH88U+EJyPCHTq6xgIcmIheMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}