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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '997e5f10c39ee447423f7d84a4d20db65ef90a8f4e0ce183e062e6254da26755' 
  AND token = 'm0IMUJYC8z4vMezOyvanp+DFbBXLrs7k+tMqVOYe2Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}