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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '99781930184d400324bfa4dd6a0f34f7eaffde49453b6797430a849dfaec2af3' 
  AND token = 'nWMCDdbgWE+4r6bShrC8Jh/BswWc3ws+XlZdExwnoB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}