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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '05b49d673abe6a8be7620fc862e5799dd3c042ebf1a02e993ebcb897367efe69' 
  AND token = 'wUdda73+QoGFFnVqJ18pU0cYz8MJdZeaTMvnLd2lT2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}