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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '859210552e65a56fd3eef2bbe0f3f24bc9c356ddb11ef3a21931f4a4be28b1a7' 
  AND token = 'M4ZpwoxIFigxplkDbctt9RgUjviJDcv7kWugWZF3NDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}