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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '05ac954186869ff4591113fa102e0f5366e1ab4c6889bdece56bc3bbacb7b97d' 
  AND token = '1UfVX+3Ca4xJrzdOoiNjeSFlZbdwUg+V1FH4n9Dd2n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}