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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1833925802fe639bf0ee9da80d970dee52f2578913fecc1a1b04cae250a990aa' 
  AND token = '4Mzr9QI0z+IPdpSkLELh4DO+Ay1UgZ1mHpOsvZtGZB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}