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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'de0fea36d07349d65522869602f6fbcabe49598e04f15d3723190f3b1c8dacbe' 
  AND token = 'bsMufrjM+zgggsaezdsrrFTiti4MVKIZ74SLI+JdwFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}