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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'fd78b46c54a8814c363691f20ad5d59fef0e96e0374d563892ee9419b37eedd0' 
  AND token = 'IUfC4zznHYaIWZ5I2aYmnNAapjiQUgDKrs7tOMi90aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}