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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd99d53cbed392fad4d046278cd40dcb0a3fe3ea7a7ae7fda2c270bb3a1d279d5' 
  AND token = 'orn3DMznR8E3E15+c1v0A154IFqjDQSnXnvYCV0ruuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}