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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5ea87438473ce1b9de566e01716d377981d74b069071eb8722971f07a6b456dd' 
  AND token = '3pn1Z0EeyUvrsVJtlDA+bDfiZ3hBLLmTAXo1tLszuXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}