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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '43c9e78e6b6abd1a91cb59a65f27392df3e5292b730d29cde1e2ac382372947f' 
  AND token = 'TkUx2to6xzoGyfP41030vezeXoGXWM3umcvuOllluYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}