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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e7e00a07a2ac698324b440cef5e9d45076abfdfacb73773b771028a59f514687' 
  AND token = 'yMR50rT1jJ9U5Md/2Xp3POcyLrGNuX4JF9MsE0kFjPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}