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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '49303b6c5515b9b6952c7668a4cc4e61740325d64de084de3ca8066fd0227f37' 
  AND token = 'YNqAsWUkoEoc/79C5Xfj/nxVneq6IyR06xq0MoH3IYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}