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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'fca8245e4a9b618bfe778f6637a734f0011eb14d4f428c990e7a1625127aa50b' 
  AND token = 'ydDG84bggfxymFAM7YuRck7DvFbtvzP3nx9k+fHZAGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}