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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1f2727d2da6b20de81f8e8dace286d930078c7aebe6e86d0702aa158a948d1fa' 
  AND token = '4uTNkkRyaxoDMBgEifQhbPnQ/RCBc7Xt9lqSxxhGbqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}